I like how you've incorporated once again the correlating animal's anatomy into C'thulu's design. I like the extension of the fingers and the contour of the thigh and calf, as well as the reflection and contrast of the eye. Although unbalanced, there is an interesting use of negative space to depict more of a void or emptiness, but the sensation of not being too far away. Will you being doing anymore illustrations of C'thulu?
I do not do didgital work but I know this type of didgital work is very similar to traditional drawing and painting so I can comment . Very nice creature design, color scheme, anatomy. All around nice work.